Triple overlapping genes
نویسندگان
چکیده
منابع مشابه
Overlapping genes and information theory.
The discovery of overlapping genes in the viruses 4 x 1 7 4 and SV40 has generated a number of interesting questions. Here we are concerned with the contribution of information theory to the analysis of overlapping genes. The purpose of this letter is to comment on Yockey's 1979 application of information theory to these problems.
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Overlapping genes in mammalian genomes are unexpected phenomena even though hundreds of pairs of protein coding overlapping genes have been reported so far. Overlapping genes can be divided into different categories based on direction of transcription as well as on sequence segments being shared between overlapping coding regions. The biologic functions of natural antisense transcripts, their i...
متن کاملThe combinatorics of overlapping genes.
Overlapping genes exist in all domains of life and are much more abundant than expected upon their first discovery in the late 1970s. Assuming that the reference gene is read in frame +0, an overlapping gene can be encoded in two reading frames in the sense strand, denoted by +1 and +2, and in three reading frames in the opposite strand, denoted by -0, -1, and -2. This motivated numerous resear...
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iii Acknowledgments I thank Dr. Giddy Landan for his advice and discussions over many cups of coffee. I thank Dr. Jeff Morris for precious help in matters statistical, philosophical, and theological. I thank Dr. Eran Elhaik and Nicholas Price for enjoyable collaborations. members, for their help and advice. I thank Hoang Hoang and Itala Paz for their tremendous support with numerous cases of co...
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When the same sequence of nucleotides codes for regions of more than one functional polypeptide, this sequence contains overlapping genes. Overlap is most common in rapidly evolving genomes with high mutation rates such as viruses, bacteria, and mitochondria. Overlap is thought to be important as: (1) a means of compressing a maximum amount of information into short sequences of structural gene...
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ژورنال
عنوان ژورنال: Nature
سال: 1978
ISSN: 0028-0836,1476-4687
DOI: 10.1038/272492a0